Cell Lines and Cell Cultures
Thermo Scientific™ GeneBLAzer™ Gqi5-NFAT-bla FreeStyle™ 293F Cells
GeneBLAzer™ Gqi5-NFAT-bla FreeStyle™ 293F cells contain the chimeric G-protein Gqi5 stably integrated into the CellSensor™ NFAT-blaFreeStyle™ 293F cell line.
Thermo Scientific™ CellSensor™ SBE-bla HEK 293T Cell Line
Smad cell signaling is a critical pathway involved in cell growth and proliferation.
Thermo Scientific™ Tango™ EDG6-bla U2OS Cells
The Tango™ EDG6-bla U2OS cells contain the human Endothelial Differentiation, Lysophosphatidic Acid G-protein-coupled Receptor, 6 (EDG6) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line.
Thermo Scientific™ LanthaScreen™ ATF2 (19-106) A549 Cell Line
Contains a fusion protein consisting of GFP and a fragment encoding for aa 19-106 of ATF2 under the control of a CMV promotor
Thermo Scientific™ CellSensor™ GAS-bla ME-180 Cell Line
The CellSensor™ GAS-bla ME-180 cell line contains a beta-lactamase reporter gene under control of the Gamma Activated Sequence (GAS) response element stably integrated into ME-180 cells.
Thermo Scientific™ CellSensor™ TNFa-bla THP-1 Cell Line
Tumor necrosis factor-alpha (TNFα) cytokine cell signaling is a critical pathway involved in immune and inflammatory responses. In addition, TNFα has been shown to inhibit growth and induce differentiation in tumor and non-tumor cells.
Thermo Scientific™ GeneBLAzer™ FXR-UAS-bla HEK 293T Cells
FXR-UAS-bla HEK 293T 293 cells contain the ligand-binding domain (LBD) of the human farnesoid X receptor (FXR) fused to the DNA-binding domain of GAL4 stably integrated in the GeneBLAzer™UAS-bla HEK 293T cell line.
Thermo Scientific™ Tango™ CXCR6-bla U2OS Cells
The Tango™ CXCR6-bla U2OS cells contain the human Chemokine (C-X-C motif) receptor 6 (CXCR6) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line.
Thermo Scientific™ Tango™ HTR2A-bla U2OS Cells
The Tango™ HTR2A-bla U2OS cells contain the human Serotonin Type 2A receptor (HTR2A) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line.
Thermo Scientific™ GeneBLAzer™ CNR1-Gα15-NFAT-bla CHO-K1 Cells
GeneBLAzer™ CNR1-Gα15-NFAT-bla CHO-K1 cells contain the human Cannabinoid Receptor 1 (CNR1) stably integrated into the GeneBLAzer™ Gα15-NFAT-bla CHO-K1 cell line.
Thermo Scientific™ Tango™ CXCR2-bla U2OS Cells
The Tango™ CXCR2-bla U2OS cells contain the Chemokine (C-X-C motif) Receptor 2 (CXCR2) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line.
Thermo Scientific™ GeneBLAzer™ OPRK1-Gqo5-NFAT-bla CHO-K1 Cells
The GeneBLAzer™ OPRK-1-Gqo5-NFAT-bla CHO-K1 cells contain the human Opioid Receptor Kappa 1 (OPRK1) (Accession No. NM_000710) stably integrated into the GeneBLAzer™ Gqo5-NFAT-bla CHO-K1 cell line.
Thermo Scientific™ Tango™ CMKLR1-bla U2OS Cells
The Tango™ CMKLR1-bla U2OS cells contain the human Chemokine like receptor 1 (CMKLR1) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line.
Thermo Scientific™ GeneBLAzer™ EDG7-NFAT-bla HEK 293T Cells
GeneBLAzer™ EDG7-NFAT-bla HEK293T cells contain the human Endothelial Differentiation Gene (EDG7) stably integrated into the CellSensor™ NFAT-bla HEK293T cell line.
Thermo Scientific™ Tango™ EDG1-bla U2OS Cells
The Tango™ EDG1-bla U2OS cells contain the human Endothelial Differentiation, Sphingolipid G-protein-coupled Receptor, 1 (EDG1) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line.